Zenbio Human AB serum is Off the clot and pooled, and provided sterile filtered and frozen. Human AB serum offers a technical advantage over animal serum when culturing a variety of human cell types, especially those cells making up the immune system. This is also the serum of choice when developing tissue engineered and regenerative medicine products, as many regulatory agencies in a growing number of countries are restricting the use of animal serum during the manufacturing process.
Since human serum from type AB donors is lacking in antibodies towards the A and B blood-type antigens, this is the type most commonly used as immunoreactivity is minimized against the human cells in culture. Male donor serum is preferred over female, as this lowers the risk of major histocompatibility class (MHC) antibodies being present. Women having a past pregnancy may have developed these antibodies to MHC antigens carried on the father’s cells or the developing fetus. If you require serum from Male donors, please see Human AB Serum Male donor.
* All samples are collected in FDA licensed facility and pathogen tested according to FDA guidelines for the following: HBsAG, Anti-HCV, Anti-HIV-1/2, HIV-1 RNA, HBV DNA, HCV RNA, Syphilis. *