Description: Herniarin is a natural coumarin occurs in some flowering plants, with antitumor effect.
In Vitro: Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 µM. Herniarin (100 µM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5 µg/mL cisplatin, Herniarin (80 µg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
|Solubility||DMSO: ≥ 125 mg/mL|
|Contents||1 vial supplied at requested quantity.|