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AS 602801
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AS 602801

$329.00$2,031.00

AS 602801 (Bentamapimod) is a novel, orally active inhibitor of JNK1.

AS601245
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AS601245

$85.00$1,149.00

AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK) (hJNK1: IC50=150nM, hJNK2: IC50=220nM and hJNK3: IC50=70 nM), has neuroprotective properties.

AS703026
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AS703026

$85.00$393.00

AS703026 (Pimasertib) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 ?M in MM cell lines.

AZ 628
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AZ 628

$113.00$519.00

AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.

AZD8330
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AZD8330

$169.00$1,345.00

AZD8330 (ARRY-424704; ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM.

B-Raf IN 1
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B-Raf IN 1

$371.00$2,250.00

B-Raf IN 1 is a highlt potent and selective B-Raf inhibitor with IC50 of 24 nM; equipotent against c-Raf (IC50= 25 nM).

B-Raf inhibitor
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B-Raf inhibitor

$466.00$1,600.50

A B-Raf inhibitor, pyrazine and pyrrolo[2,3-b]pyridine derivatives, useful in the treatment of cancer and proliferative diseases.

B-Raf inhibitor 1
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B-Raf inhibitor 1

$155.00$1,205.00

B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.

B-Raf inhibitor 1 (dihydrochloride)
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B-Raf inhibitor 1 (dihydrochloride)

$190.00$2,213.00

B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.

BI-D1870
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BI-D1870

$197.00$778.00

BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3?, MARK3, CK1 and Aurora B.

BIX 02565
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BIX 02565

$281.00$2,115.00

BIX 02565 is a novel ribosomal S6 kinase 2 (RSK2) inhibitor with an IC50 of 1.1 nM.

BIX02188
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BIX02188

$205.00$1,969.00

BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.