Showing 1–12 of 181 results

Show sidebar
2-(2-Amino-3-methoxyphenyl)-4H-chromen-4-one Chemical Structure Picture
Close

2-(2-Amino-3-methoxyphenyl)-4H-chromen-4-one

$85.00$310.00

PD98059 is a MEK inhibitor with IC50 of 5 μM, also suppresses TCDD binding to the aryl hydrocarbon receptor (AHR) with IC50 of 4 μM.

5Z-7-Oxozeaenol Chemical Structure Picture
Close

5Z-7-Oxozeaenol

$207.00$810.00

5Z-7-Oxozeaenol is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC50s of 8 nM and 52 nM, respectively.

Acumapimod Chemical Structure Picture
Close

Acumapimod

$166.00$2,001.00

Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 μM for p38α.

AD80 Chemical Structure Picture
Close

AD80

$99.00$2,822.00

AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTOR activity.

AG126 Chemical Structure Picture
Close

AG126

$117.00$1,357.00

AG126 is a tyrosine kinase inhibitor which can prevent the activation of mitogen-activated protein kinase p42MAPK (ERK2).

Anisomycin Chemical Structure Picture
Close

Anisomycin

$85.00$246.00

Anisomycin is a potent c-Jun N-terminal kinase (JNK) activator.

APS-2-79 Chemical Structure Picture
Close

APS-2-79

$85.00$649.00

APS-2-79 behaves as a kinase suppressor of Ras (KSR)-dependent antagonist of RAF-mediated MEK phosphorylation. APS-2-79 binds directly to KSR2 within the KSR2-MEK1 complex with an IC 50 of 120±23 nM for KSR2.

APS-2-79 (hydrochloride) Chemical Structure Picture
Close

APS-2-79 (hydrochloride)

$117.00$1,051.00

APS-2-79 hydrochloride behaves as a kinase suppressor of Ras (KSR)-dependent antagonist of RAF-mediated MEK phosphorylation. APS-2-79 binds directly to KSR2 within the KSR2-MEK1 complex with an IC 50 of 120±23 nM for KSR2.

APTO-253 Chemical Structure Picture
Close

APTO-253

$134.00$939.00

APTO-253 is an inducer of Kruppel-like factor 4 (KLF4), and also stabilizes Gquadruplex, with anti-proliferative activity.

AS 602801 Chemical Structure Picture
Close

AS 602801

$366.00$2,323.00

AS 602801 is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.

AS601245 Chemical Structure Picture
Close

AS601245

$85.00$1,308.00

AS601245 is a JNK Inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively.

AS703026 Chemical Structure Picture
Close

AS703026

$85.00$439.00

AS703026 is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2, used for cancer treatment.