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ABT-348 Chemical Structure Picture
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ABT-348

$939.00$5,559.00

ABT-348 is is an ATP-competitive multitargeted kinase inhibitor with IC50s for inhibiting binding Aurora B (7 nM), C (1 nM), and A (120 nM), and also inhibits RET tyrosine kinase, PDGFRβ, and Flt1 with IC50s of 7 nM, 3 nM and 32 nM.

ABT-751 Chemical Structure Picture
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ABT-751

$134.00$729.00

ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively.

Acelarin Chemical Structure Picture
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Acelarin

$181.00$3,386.00

Acelarin (NUC-1031) is a ProTide transformation and enhancement of the widely-used nucleoside analogue, gemcitabine.

ACY-1215 Chemical Structure Picture
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ACY-1215

$72.00$180.00

ACY-1215 is a potent and selective HDAC6 inhibitor, with an enzymatic IC50 value of 5 nM. ACY-1215 also inhibits HDAC1, HDAC2, and HDAC3 with IC50 of 58, 48, and 51 nM, respectively.

ACY-738 Chemical Structure Picture
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ACY-738

$166.00$1,051.00

ACY-738 is a potent, selective and orally-bioavailable HDAC6 inhibitor, with an IC50s of 1.7 nM; ACY-738 also inhibits HDAC1, HDAC2, and HDAC3, with IC50s of 94, 128, and 218 nM.

ACY-775 Chemical Structure Picture
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ACY-775

$149.00$1,115.00

ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6) with an IC50 of 7.5 nM.

Adenine Chemical Structure Picture
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Adenine

$85.00$102.00

Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry.

Adenosine Chemical Structure Picture
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Adenosine

$85.00$134.00

Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.

AG14361 Chemical Structure Picture
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AG14361

$223.00$2,155.00

AG14361 is a potent PARP-1 inhibitor, with a Ki of < 5 nM, and in permeabilized SW620 and intact SW620 cells, the IC50s are 29 nM and 14 nM, respectively.

AGK2 Chemical Structure Picture
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AGK2

$134.00$503.00

AGK2 is a selective SIRT2 inhibitor with IC50 of 3.5 μM. AGK2 can also inhibit SIRT1 and SIRT3 with IC50 of 30 and 91 μM, respectively.

AK-1 Chemical Structure Picture
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AK-1

$85.00$488.00

AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor.

AK-7 Chemical Structure Picture
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AK-7

$181.00$971.00

AK-7 is a selective cell- and brain-permeable SIRT2 inhibitor, with an IC50 of 15.5 μM.