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(-)-JQ-1
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(-)-JQ-1

$253.00$7,500.00

(-)-JQ-1, the stereoisomer (+)-JQ1, showed no significant interaction with any bromodomain; (+)-JQ1 is an inhibitor for the BET.

(+)-JQ-1
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(+)-JQ-1

$113.00$7,015.00

(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4 (1/2).

10-Deacetyl-7-xylosyl paclitaxel
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10-Deacetyl-7-xylosyl paclitaxel

$147.00$343.00

10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility.

17-AAG
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17-AAG

$99.00$505.00

17-AAG (NSC 330507; CP 127374) is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.

17-AAG (Hydrochloride)
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17-AAG (Hydrochloride)

$99.00$505.00

17-AAG Hcl is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.

3-Deazaneplanocin A
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3-Deazaneplanocin A

$554.00$1,016.00

3-Deazaneplanocin A (DZNep) is an attractive epigenetic anticancer agent through the inhibition of the cellular enhancer of zeste homolog 2 (EZH2) protein.

3-Deazaneplanocin A (hydrochloride)
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3-Deazaneplanocin A (hydrochloride)

$141.00$477.00

3-Deazaneplanocin A hydrochloride (DZNep hydrochloride) is an attractive epigenetic anticancer agent through the inhibition of the cellular enhancer of zeste homolog 2 (EZH2) protein.

360A
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360A

$295.00$1,975.00

360A is a strong affinity and selectivity inhibitor of G-quadruplex structures.

360A (iodide)
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360A (iodide)

$295.00$1,975.00

360A is a strong affinity and selectivity inhibitor of G-quadruplex structures.

4'-Demethylepipodophyllotoxin
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4′-Demethylepipodophyllotoxin

$105.00$126.00

4′-Demethylepipodophyllotoxin (4′-DMEP) is a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer drugs; a potent inhibitor of microtubule assembly.

4SC-202
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4SC-202

$155.00$1,205.00

4SC-202 is an orally available potent HDACi specific for class I
HDAC isoenzymes (NO HDAC8) with IC50s of 1.2/1.12/0.57 uM for HDAC1/2/3; high selectivity over ClassIIa/IIb/III HDACs.

4SC-202 (free base)
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4SC-202 (free base)

$155.00$1,205.00

4SC-202 free base is an orally available potent HDACi specific for class I HDAC isoenzymes (NO HDAC8) with IC50s of 1.2/1.12/0.57 uM for HDAC1/2/3; high selectivity over ClassIIa/IIb/III HDACs.