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(3R,4S)-Tofacitinib

$4,030.00

(3R,4S)-Tofacitinib is an enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.

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(3S,4R)-Tofacitinib

$4,030.00

(3S,4R)-Tofacitinib is an enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.

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(3S,4S)-Tofacitinib

$4,030.00$4,432.00

(3S,4S)-Tofacitinib is the S-enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.

1-(4-Methoxybenzyl)-3-(5-nitrothiazol-2-yl)urea Chemical Structure Picture
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1-(4-Methoxybenzyl)-3-(5-nitrothiazol-2-yl)urea

$85.00$347.00

AR-A014418 is a selective, effective and ATP-competitive GSK3β inhibitor with an IC50 value of 104 nM, and has no significant inhibition on 26 other kinases.

Adavivint Chemical Structure Picture
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Adavivint

$608.00$3,427.00

Adavivint is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells.

AG-490 Chemical Structure Picture
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AG-490

$72.00$274.00

AG-490 is an tyrosine kinase inhibitor, inhibits EGFR and Stat-3.

AG126 Chemical Structure Picture
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AG126

$117.00$1,357.00

AG126 is a tyrosine kinase inhibitor which can prevent the activation of mitogen-activated protein kinase p42MAPK (ERK2).

Alantolactone Chemical Structure Picture
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Alantolactone

$85.00$729.00

Alantolactone(Alant camphor) is a sesquiterpene lactone; has potential activity against triple-negative breast cancer MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3) signaling pathway.

Artesunate Chemical Structure Picture
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Artesunate

$85.00$134.00

Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1).

AS1517499 Chemical Structure Picture
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AS1517499

$198.00$1,615.00

AS1517499 is a potent STAT6 inhibitor with IC50 of 21 nM.

Asiaticoside Chemical Structure Picture
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Asiaticoside

$72.00$421.00

Asiaticoside, a trisaccaride triterpene from Centella asiatica, suppresses TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts; Asiaticoside shows antioxidant, anti-inflammatory, and anti-ulcer properties.

Astragaloside IV Chemical Structure Picture
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Astragaloside IV

$85.00$391.00

Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.