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(-)-Epigallocatechin Gallate Chemical Structure Picture
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(-)-Epigallocatechin Gallate

$72.00$92.00

(-)-Epigallocatechin Gallate is an antioxidant polyphenol flavonoid form green tea, and inhibits the activation of EGFR, HER2 and HER3, with antitumor activity.

(±)-Zanubrutinib Chemical Structure Picture
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(±)-Zanubrutinib

$125.00$1,884.00

(±)-Zanubrutinib is a potent, selective and orally available Bruton’s tyrosine kinase (Btk) inhibitor.

1-Naphthyl PP1 Chemical Structure Picture
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1-Naphthyl PP1

$125.00$1,454.00

1-Naphthyl PP1(1-NA-PP 1) is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively).

1-Naphthyl PP1 (hydrochloride) Chemical Structure Picture
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1-Naphthyl PP1 (hydrochloride)

$125.00$1,454.00

1-Naphthyl PP1(1-NA-PP1) hydrochloride is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively).

2
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2,4-Pyrimidinediamine with linker

$568.00$3,386.00

2,4-Pyrimidinediamine with linker is a patent compound in WO2013055780A1, Page 71; multikinase inhibitor and has a -NH2 terminal linker for further synthesis.

5Z-7-Oxozeaenol Chemical Structure Picture
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5Z-7-Oxozeaenol

$207.00$810.00

5Z-7-Oxozeaenol is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC50s of 8 nM and 52 nM, respectively.

7-Hydroxy-4-chromone Chemical Structure Picture
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7-Hydroxy-4-chromone

$72.00$79.00

7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM.

A 419259 Chemical Structure Picture
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A 419259

$295.00$1,019.00

A 419259 is a broad-spectrum pyrrolo-pyrimidine inhibitor, designed to enhance selectivity towards the Src family with IC50 of 9 nM, <3 nM and <3 nM for Src, Lck and Lyn, respectively.

A 419259 (trihydrochloride) Chemical Structure Picture
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A 419259 (trihydrochloride)

$295.00$1,019.00

A 419259 trihydrochloride is a broad-spectrum pyrrolo-pyrimidine inhibitor, designed to enhance selectivity towards the Src family with IC50 of 9 nM, <3 nM and <3 nM for Src, Lck and Lyn, respectively.

A-770041 Chemical Structure Picture
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A-770041

$435.00$729.00

A-770041 is selective and orally active Src-family Lck inhibitor; A-770041 is a 147 nM inhibitor of Lck (1 mM ATP) and is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling.

ABT-348 Chemical Structure Picture
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ABT-348

$939.00$5,559.00

ABT-348 is is an ATP-competitive multitargeted kinase inhibitor with IC50s for inhibiting binding Aurora B (7 nM), C (1 nM), and A (120 nM), and also inhibits RET tyrosine kinase, PDGFRβ, and Flt1 with IC50s of 7 nM, 3 nM and 32 nM.

AC710 Chemical Structure Picture
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AC710

$230.00$2,500.00

AC710 is a potent PDGFR inhibitor with Kds of 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRα and PDGFRβ, respectively.