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SN50 Chemical Structure Picture
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SN50

$149.00$585.00

SN50 is a cell permeable inhibitor of NF-κB translocation.

Stachydrine Chemical Structure Picture
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Stachydrine

$85.00$230.00

Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis.

Sulfasalazine Chemical Structure Picture
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Sulfasalazine

$85.00$134.00

Sulfasalazine is a drug for the treatment of rheumatoid arthritis and ulcerative colitis. Sulfasalazine is reported to suppress NF-κB activity.

Takinib Chemical Structure Picture
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Takinib

$113.00$2,084.00

Takinib is a potent and selective TAK1 inhibitor with an IC50 of 9.5 nM.

TBK1/IKKε-IN-1 Chemical Structure Picture
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TBK1/IKKε-IN-1

$877.00$3,494.00

TBK1/IKKε-IN-1 is a dual TBK1 and IKKε inhibitor extracted from patent US20160376283 A1, Compound 274 in Example 60, has IC50s of <100 nM.

TBK1/IKKε-IN-2 Chemical Structure Picture
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TBK1/IKKε-IN-2

$568.00$3,386.00

TBK1/IKKε-IN-2 is a dual TBK1 and IKKε inhibitor.

Tomatidine Chemical Structure Picture
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Tomatidine

$85.00$230.00

Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling.

TPCA-1 Chemical Structure Picture
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TPCA-1

$128.00$802.00

TPCA-1 is a potent and selective inhibitor of IKK-2 with IC50 of 17.9 nM.

WAY-204688 Chemical Structure Picture
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WAY-204688

$939.00$5,559.00

WAY-204688 is an estrogen receptor (ER-α) selective, orally active inhibitor of NF-κB transcriptional activity with an IC50 of 122 ± 30 nM for NF-κB-luciferase (NF-κB-luc) in HAECT-1 cells.

Withaferin A Chemical Structure Picture
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Withaferin A

$125.00$461.00

Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities.

Yangonin Chemical Structure Picture
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Yangonin

$230.00$359.00

Yangonin exhibits affinity for the human recombinant cannabinoid CB1 receptor with an IC50 and a Ki of 1.79 ± 0.53 μM and 0.72±0.21 μM, respectively.

α-Lipoic Acid Chemical Structure Picture
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α-Lipoic Acid

$85.00$93.00

α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation.