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Pentosan Polysulfate Chemical Structure Picture
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Pentosan Polysulfate

$117.00

Pentosan Polysulfate is a semi-synthetic drug used to treat various medical conditions including thrombi and interstitial cystitis.

PS-1145 Chemical Structure Picture
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PS-1145

$158.00$1,695.00

PS-1145 is an IκB kinase (IKK) inhibitor with an IC50 of 88 nM.

Pyrrolidinedithiocarbamate (ammonium) Chemical Structure Picture
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Pyrrolidinedithiocarbamate (ammonium)

$85.00$93.00

Pyrrolidinedithiocarbamate ammonium is a selective NF-κB inhibitor.

QNZ Chemical Structure Picture
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QNZ

$134.00$697.00

QNZ shows strong inhibitory effects on NF-κB transcriptional activation and TNF-α production with IC50s of 11 and 7 nM, respectively. EVP4593 is a neuroprotective inhibitor of SOC channel.

Resveratrol Chemical Structure Picture
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Resveratrol

$85.00$134.00

Resveratrol is one of the numerous polyphenolic compounds found in several vegetal sources, has a wide spectrum of targets with IC50 of 0.8, 1, 3.3 and 5 μM for adenylyl cyclase, IKKβ, DNA polymerase α and δ, respectively.

RTA-408 Chemical Structure Picture
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RTA-408

$152.00$877.00

RTA-408 is an antioxidant inflammation modulator (AIM), which activates Nrf2 and suppresses nitric oxide (NO).

Saikosaponin D Chemical Structure Picture
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Saikosaponin D

$85.00$702.00

Saikosaponin D is a triterpene saponin isolated from Bupleurum, with anti-inflammatory, anti-bacterial, anti-tumor, and anti-allergic activities; Saikosaponin D inhibits selectin, STAT3 and NF-kB and activates estrogen receptor-β.

Sarsasapogenin Chemical Structure Picture
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Sarsasapogenin

$102.00$295.00

Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.

SC-514 Chemical Structure Picture
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SC-514

$102.00$391.00

SC-514 is a selective IKK-2 inhibitor (IC50=11.2±4.7 μM), which does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.

Schisantherin A Chemical Structure Picture
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Schisantherin A

$148.00$431.00

Schisantherin A is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin A inhibits p65-NF-κB translocation into the nucleus by IκBα degradation.

Shikonin Chemical Structure Picture
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Shikonin

$85.00$424.00

Shikonin is an inhibitor of TMEM16A chloride channel with an IC50 of 6.5 μM. Shikonin is also a specific inhibitor of PKM2 and can also inhibit tumor necrosis factor-α (TNF-α) and prevent activation of nuclear factor-κB (NF-κB) pathway.

Sinomenine hydrochloride Chemical Structure Picture
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Sinomenine hydrochloride

$85.00$93.00

Sinomenine hydrochloride is a blocker of the NF-κB activation and also an activator of μ-opioid receptor.