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(-)-Indolactam V Chemical Structure Picture
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(-)-Indolactam V

$246.00$890.00

(-)-Indolactam V (ILV) is a protein kinase C activator, which strongly directs human ES cell-derived definitive endoderm into pancreatic endoderm.

(+)-JQ-1 Chemical Structure Picture
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(+)-JQ-1

$117.00$8,055.00

(+)-JQ-1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for the first and second bromodomain (BRD4(1/2)).

(3R
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(3R,4S)-Tofacitinib

$4,030.00

(3R,4S)-Tofacitinib is an enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.

(3S
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(3S,4R)-Tofacitinib

$4,030.00

(3S,4R)-Tofacitinib is an enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.

(3S
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(3S,4S)-Tofacitinib

$4,030.00$4,432.00

(3S,4S)-Tofacitinib is the S-enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.

(R)-(-)-JQ1 Enantiomer Chemical Structure Picture
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(R)-(-)-JQ1 Enantiomer

$198.00$1,937.00

(-)-JQ-1 is the stereoisomer of (+)-JQ1. (+)-JQ1 potently decreases expression of both BRD4 target genes, whereas (−)-JQ1 has no effect.

[6]-Gingerol Chemical Structure Picture
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[6]-Gingerol

$85.00$702.00

[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

3-Deazaneplanocin A Chemical Structure Picture
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3-Deazaneplanocin A

$625.00$1,156.00

3-Deazaneplanocin A is a potent histone methyltransferase EZH2 inhibitor.

3-Deazaneplanocin A (hydrochloride) Chemical Structure Picture
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3-Deazaneplanocin A (hydrochloride)

$149.00$1,454.00

3-Deazaneplanocin A hydrochloride is a potent histone methyltransferase EZH2 inhibitor.

3-TYP Chemical Structure Picture
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3-TYP

$102.00$793.00

3-TYP is a selective SIRT3 inhibitor, with an IC50 of 16 nM, more potent over SIRT1 (IC50=88 nM), SIRT2 (IC50=92 nM).

4SC-202 Chemical Structure Picture
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4SC-202

$166.00$1,373.00

4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).

4SC-202 (free base) Chemical Structure Picture
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4SC-202 (free base)

$166.00$1,373.00

4SC-202 (free base) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).