Showing 1–12 of 809 results

Show sidebar
(+)-BAY-1251152 Chemical Structure Picture
Close

(+)-BAY-1251152

$181.00$1,437.00

(+)-BAY-1251152 is a CDK9 inhibitor extracted from patent WO 2014076091 A1, example 1.

(±)-10-Hydroxycamptothecin Chemical Structure Picture
Close

(±)-10-Hydroxycamptothecin

$72.00$152.00

(±)-10-Hydroxycamptothecin, an indole alkaloid isolated from Camptotheca acuminate, inhibits the activity of topoisomerase I and has a broad spectrum of anticancer activity.

(20S)-Protopanaxatriol Chemical Structure Picture
Close

(20S)-Protopanaxatriol

$104.00$648.00

(20S)-Protopanaxatriol is a metabolite of ginsenoside, works through the glucocorticoid receptor (GR) and oestrogen receptor (ER), and is also a LXRα inhibitor and a PPARγ activator.

1-NM-PP1 Chemical Structure Picture
Close

1-NM-PP1

$158.00$939.00

1-NM-PP1 inhibits Cdk7 recovered from the mutant, but not the wild-type cells with an IC50 of ~50 nM with either substrate.

10-Deacetyl-7-xylosyl paclitaxel Chemical Structure Picture
Close

10-Deacetyl-7-xylosyl paclitaxel

$134.00$359.00

10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility.

10-Oxo Docetaxel Chemical Structure Picture
Close

10-Oxo Docetaxel

$442.00$2,643.00

10-Oxo Docetaxel (Docetaxel Impurity) is a novel taxoid having remarkable anti-tumor properties and a Docetaxel intermediate.

17-AAG Chemical Structure Picture
Close

17-AAG

$102.00$568.00

17-AAG is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.

17-AAG (Hydrochloride) Chemical Structure Picture
Close

17-AAG (Hydrochloride)

$102.00$407.00

17-AAG Hydrochloride is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.

2-Methoxyestradiol Chemical Structure Picture
Close

2-Methoxyestradiol

$72.00$274.00

2-Methoxyestradiol is a microtubule and HIF-1 inhibitor, binds to tubulin at or near the colchicine site and inhibits the polymerization of tubulin in vitro, works by interfering with normal microtubule function.

2'-Deoxypseudoisocytidine Chemical Structure Picture
Close

2′-Deoxypseudoisocytidine

$310.00$7,572.00

2′-Deoxypseudoisocytidine is a nucleoside analogue.

3-TYP Chemical Structure Picture
Close

3-TYP

$102.00$793.00

3-TYP is a selective SIRT3 inhibitor, with an IC50 of 16 nM, more potent over SIRT1 (IC50=88 nM), SIRT2 (IC50=92 nM).

360A Chemical Structure Picture
Close

360A

$327.00$2,259.00

360A is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC50 of 300 nM for telomerase in TRAP-G4 assay.