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(-)-Epigallocatechin Gallate Chemical Structure Picture
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(-)-Epigallocatechin Gallate

$72.00$92.00

(-)-Epigallocatechin Gallate is an antioxidant polyphenol flavonoid form green tea, and inhibits the activation of EGFR, HER2 and HER3, with antitumor activity.

(+)-JQ-1 Chemical Structure Picture
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(+)-JQ-1

$117.00$8,055.00

(+)-JQ-1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for the first and second bromodomain (BRD4(1/2)).

(2-Hydroxypropyl)-β-cyclodextrin Chemical Structure Picture
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(2-Hydroxypropyl)-β-cyclodextrin

$85.00$149.00

(2-Hydroxypropyl)-β-cyclodextrin is a widely used drug delivery vehicle to improve the stability and bioavailability.

17-AAG Chemical Structure Picture
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17-AAG

$102.00$568.00

17-AAG is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.

17-AAG (Hydrochloride) Chemical Structure Picture
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17-AAG (Hydrochloride)

$102.00$407.00

17-AAG Hydrochloride is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.

2-(2-Amino-3-methoxyphenyl)-4H-chromen-4-one Chemical Structure Picture
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2-(2-Amino-3-methoxyphenyl)-4H-chromen-4-one

$85.00$310.00

PD98059 is a MEK inhibitor with IC50 of 5 μM, also suppresses TCDD binding to the aryl hydrocarbon receptor (AHR) with IC50 of 4 μM.

2-Methoxyestradiol Chemical Structure Picture
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2-Methoxyestradiol

$72.00$274.00

2-Methoxyestradiol is a microtubule and HIF-1 inhibitor, binds to tubulin at or near the colchicine site and inhibits the polymerization of tubulin in vitro, works by interfering with normal microtubule function.

2-Morpholino-8-phenyl-4H-chromen-4-one Chemical Structure Picture
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2-Morpholino-8-phenyl-4H-chromen-4-one

$85.00$464.00

LY294002 is a broad-spectrum inhibitor of PI3K, with IC50 of 0.5/0.57/0.97 μM for PI3Kα/PI3Kδ/PI3Kβ, respectively, also potently inhibits CK2 with IC50 of 98 nM.

3-Methyladenine Chemical Structure Picture
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3-Methyladenine

$85.00$439.00

3-Methyladenine is a potent inhibitor of autophagy and PI3K, blocking autophagy through its effect on PI3K, with IC50s of 25 μM and 60 μM for Vps34 and PI3Kγ, respectively.

3BDO Chemical Structure Picture
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3BDO

$219.00$877.00

3BDO is a new mTOR activator which can also inhibit autophagy.

4-Hydroxytamoxifen Chemical Structure Picture
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4-Hydroxytamoxifen

$85.00$890.00

4-Hydroxytamoxifen, an active metabolite of tamoxifen, is a selective estrogen receptor antagonist, with an IC50 of 3.3 nM for the [3H]oestradiol binding to oestrogen receptor, widely used to treat breast cancer; 4-Hydroxytamoxifen also increases CRISPR/Cas9-mediated editing frequency.

5-Aminolevulinic acid (hydrochloride) Chemical Structure Picture
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5-Aminolevulinic acid (hydrochloride)

$110.00$407.00

5-Aminolevulinic acid HCl is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.